Born in America, Brenna studied in Boston and began his international career in 2012 when he portrayed Aron in Schönberg's "Moses und Aron" at the Zurich Opera House. He has since sung at the Met in New York, in San Francisco, Washington, La Scala in Milan, at the State Opera Houses of Munich and Stuttgart, Theater an der Wien, in Amsterdam, Bilbao, Moscow, at the Salzburg Festival, the Wagner-Tagen in Budapest and at the Ravello Festival in Italy. His repertoire includes Siegfried and Siegmund in Wagner's "Ring", Parsifal, Desportes in Zimmermann's "Die Soldaten", Laca in Janáček's "Jenufa", as well as Boris in "Katja Kabanowa", Herodes in »Salome«, Aegisth in "Elektra", Drum Major in Berg's "Wozzeck", Alwa in "Lulu", Jim Mahoney in Brecht/Weill's "Mahagonny" (a role with which he debuted in 2014 in Wiesbaden) and Eisenstein in "Die Fledermaus" (with which he debuted this year at the Deutsche Oper Berlin). In 2018 Naxos released the complete recording of "Götterdämmerung" with the Hong Kong Philharmonic Orchestra and Daniel Brenna as Siegfried. This season, he sings the role of Laca Janáček's "Jenufa" at the Wiesbaden State Theatre.